2毒死蜱和阿特拉津对蓝鳃太阳鱼.pdfVIP

Available online at Environmental Pollution 152 (2008) 217e224 /locate/envpol Examining the joint toxicity of chlorpyrifos and atrazine in the aquatic species: Lepomis macrochirus , Pimephales promelas and Chironomus tentans W. Tyler Mehler, Lance J. Schuler, Michael J. Lydy* Fisheries and Illinois Aquaculture Center and Department of Zoology, Southern Illinois University at Carbondale, Carbondale, IL 62901-6511, USA Received 27 February 2007; received in revised form 23 April 2007; accepted 26 April 2007 The joint toxicity between atrazine and chlorpyrifos caused greater than additive responses in invertebrates, but the interactions in vertebrates was less pronounced. Abstract The joint toxicity of chlorpyrifos and atrazine was compared to that of chlorpyrifos alone to discern any greater than additive response using both acute toxicity testing and whole-body residue analysis. In addition, acetylcholinesterase (AChE) inhibition and biotransformation were investigated to evaluate the toxic mode of action of chlorpyrifos in the presence of atrazine. The joint toxicity of atrazine and chlorpyrifos exhibited no significant difference in Lepomis macrochirus compared to chlorpyrifos alone; while studies performed with Pimephales promelas and Chironomus tentans, did show significant differences. AChE activity and biotransformation showed no significant differences between the joint toxicity of atrazine and chlorpyrifos and that of chlorpyrifos alone. From the data collected, the combin