加味炙甘草汤治疗窦性心动过缓的临床探究.pdfVIP

提 要 目的：通过观察加味炙甘草汤治疗气虚血瘀型窦性心动过缓的疗效，初步探讨加 味炙甘草汤治疗气虚血瘀型窦性心动过缓的作用机理。方法：将符合病例纳入标准的 60例患者随机分为试验组、对照组各30例，试验组给予加味炙甘草汤治疗，对照组 给予心宝丸治疗，4周为一疗程，观察疗效以及有无不良反应。结果：心动过缓疗效 比较：心率、心电图疗效、24h动态心电图试验组均优于对照组，两组有显著性差异 （P0.05）；临床症状疗效：试验组在改善心悸、胸闷、神疲等方面优于对照组 （P0.05）。疾病综合疗效比较：试验组显著优于对照组（P0.05）。结论：中药加 味炙甘草汤是治疗气虚血瘀型窦性心动过缓的有效方剂，对心悸、胸闷、神疲等症状 有明显的改善，能够提高窦性心率，其作用机制可能与加味炙甘草汤能提高窦房结节 律，改善心功能有关系。 关键词 加味炙甘草汤；窦性心动过缓；临床研究 The clinical research of Modified Zhigancao Soup on the treatment of sinus bradycardia Speciality: Internal Medicine of Traditional Chinese Medicine Author : Luo Chuanchao Tutor: Pro.Zhang Shiliang Abstract Objective: To observe the clinical curative effect of treating syndrome of Qi-asthenia and blood-Stasis of sinus bradycardia through applying the Modified Zhigancao Soup and To explore its mechanism.Methods: 60 patients were randomly divided into the experimental group (30 cases) and the control group (30 cases). Xinbao pill were given to the control group. The experimental group was dosed Modified Zhigancao Soup. The course of clinical treatment is four weeks.Result: Compared with the control group, experimental group after treatment had remarkable effect upon improving electrocardiogram, 24 hours dynamic electrocardiogram (DCG)and heart rates. There were significant differences (P0.05).The effect on clinical symptom of The experimental group ,including palpitation,chest distress and lassitude, was greatly improved(P0.05). The experimental group had remarkable effect upon clinical general therapeutic effect （P0.05 ）.Conclusion: Modified Zhigancao Soup has good curative effect on treating syndrome of Qi-asthenia and blood-Stasis