参芪正颜饮治疗Bell麻痹的临床探究.pdfVIP

提 要 目的：本研究拟通过中药以参芪正颜饮为主配合基础治疗（肌注维生素B 类+针 刺治疗）与基础治疗组相对照，观察中药参芪正颜饮治疗 Bell 麻痹的临床疗效，旨 在探讨中西医结合方法综合治疗 Bell 麻痹的作用机理，以期寻求出治疗 Bell 麻痹的 新思路和有效方药，并为以后进行更为严格的多中心随机对照试验提供依据。方法： 临床研究，将 55 例 Bell 麻痹患者随机分为参芪正颜饮治疗组与基础治疗对照组，两 组均治疗 28 天。观察治疗前后两组 House-Brackmann （H–B ）分级、面神经功能评 定表等指标的变化。结果：经统计学分析，治疗组总有效率达 96.4 ％，对照组总有效 率为 88.9 ％，两组比较总有效率有显著性差异（P ＜0.05 ）。治疗后，治疗组在 H–B 分级、面神经功能评定表量化指标的改善方面均优于对照组（P ＜0.05 ）。结论：以参 芪正颜饮加减为主的中西医结合治疗在改善患者面神经功能方面具有一定优势，能通 过健脾益气扶正、祛邪活血通络等作用起到活血抗炎、改善微循环并提高机体免疫力， 达到既能增强临床疗效、缩短病程、提高患者生活质量，同时又可减少副作用、改善 预后，是 Bell 麻痹的优选治疗手段。 关键词 Bell 麻痹；参芪正颜饮；House-Brackmann 分级量表；中西医结合治疗； 临床研究 The Clinical Research on Shen Qi Zheng Yan Yin in Treating Bell’s Palsy Speciality：Clinical basic research of Traditional Chinese Medicine Author ：Liu Wenbin Tutor ：Prof ．Huo Qing Abstract Objective：This study tries to use Shen Qi Zheng Yan Yin as primary cure and cooperate with based treatment (muscle inject VitB classes + acupuncture therapy )to compare with based treatment group, observes the evaluation of Bell’s Palsy by Shen Qi Zheng Yan decoction, aiming to the therapeutic effect of treatment of integrated traditional Chinese and western medicine the mechanism of action of Bell paralysis, thus seek to new ideas 、 an effective agent on treating Bell’s Palsy and underlie the more strict for later multicenter randomized controlled study trials.Methods ：Clinical research 55 patients with Bells palsy patients were divided into Shen Qi Zheng Yan decoction treatment group and control group randomly, both groups cure 28 days. Then we observes before and after treatment two groups - House-Brackmann (H - B) hierarchical, Facial nerve function evaluation table etc, indexes to ch