绝经女性颈动脉粥样硬化的病机探讨及证候临床调研.pdfVIP

提 要 目的：探讨绝经女性 CAS 的病机与证候分布，做好绝经女性 CAS 的诊疗及预防 工作，发挥中医药的优势，为更好地预防中风病进行探索。方法：采集临床绝经女 性 CAS 患者的相关信息，运用统计学方法对患者的症状、病史及相关资料进行分 析，筛选绝经女性 CAS 的危险因素，初步总结绝经女性 CAS 的病机及证候分布规 律。结果：①增龄、雌激素缺乏、鼾眠、嗜咸、辛辣、被动吸烟、超重、腹型肥 胖、高血压病史、高脂血症病史是绝经女性 CAS 主要的危险因素；②绝经女性组与 正常生育期女性组在雌激素水平、打鼾程度、肥胖、高血压、高血脂、颈动脉粥样 硬化程度方面具有显著差异；③证候分布在绝经早期以火热证居多，随着绝经年限 的延长，雌激素水平降低，肝肾阴虚证的程度愈甚。结论：提出“脏腑虚损，天癸 告竭，肝肾亏虚，阴阳失调，痰火瘀浊湿邪，结于人迎脉，形成人迎脉积”的绝经 女性颈动脉粥样硬化症病机理论。绝经女性 CAS 的证候分布以火热证及肝肾阴虚证 居多，在绝经早期以火热证为主，痰瘀是兼夹邪气。随着绝经年限的延长，雌激素 水平的下降，火热证的程度降低，肝肾阴虚证的程度愈甚。 关键词 绝经女性；颈动脉粥样硬化；肝肾阴虚；火热；临床调研 Pathogenesis exploring and Clinical study on syndrome of Carotid artery atherosclerosis(CAS) in menopausal women Specialty: the study of neuro-medical disease clinical of TCM Author: Chen Yan Tutor: Prof. DING Yuanqing Abstract Purpose: This paper is designed to explore the pathogenesis and the distribution rule of syndrome of CAS in menopausal women. In addition, it is intended to perfect the dia- gnosis, therapy and prevention of CAS in menopausal women, aiming to play the advant- age of Traditional Chinese Medicine and explore the prevention of stoke. Methods: After clinically acquiring the information of the menopausal women patients with CAS,we analyze the patients symptoms, medical history and related data by statistical methods, filter the risk factors of CAS, and preliminarily summary the pathogenesis and the distribution rule of syndrome of CAS in menopausal women. Results ：(1) The risk factors of CAS,such as age, deficiency of estrogen, snoring sleep, salty, spice,passive smoking, obesity, history of hypertension, history of hyperlipidemia are main in menopausal women.(2