磁共振灌注成像对肝癌介入治疗疗效评价.pdfVIP

放射学实践 2008 年 6 月第 23 卷第 6 期 Radiol Practice ,lun 2008 ,Vol 23 ,No. 6 679 ·介入放射学· 磁共振灌注成像对肝癌介入治疗疗效评价 陈望，郭友，郑晓林，唐承富，何惜金 E摘要】 目的:探讨 PWI 在评估肝癌介入治疗的局部疗效中的价值。方法:搜集 36 例肝癌患者，经肝动脉化疗检塞 及微波消融术后，行磁共振灌注成像，对比残留肿瘤与良性强化组织的量化结果，并评价灌注成像诊断准确性。结果:介 入治疗术后残留肿瘤及良性强化区的最大增强斜率(MSD 差异有显著性意义;残留或复发肿瘤的时间一信号强度曲线为快 速上升型;良性强化组织的时间-信号强度曲线为缓慢上升型;PWI 对肝脏介入治疗后肿瘤残留、复发检测的敏感度为 0.89. 特异度为 O. 73 。结论:PWI 对肝脏肿瘤介入治疗术后的组织类型区别是一种非常敏感的功能成像技术，能够在肝 癌介入治疗术后病变的早期发现肿瘤残留及复发。 E关键词】 磁共振成像;灌注;肝肿瘤;放射摄影术，介入性 E 中图分类号】 R445.2: R735. 7: R815 【文献标识码】 A [文章编号】 1000-0313(2008)06-0679-04 Value of MR Perfusion Imaging after Interventional Treatment of Liver Cancer CHEN Zhao.GUO Yo口 .ZHENG Xiao-lin.et a l. Department of Radiology. Dongguan People s Hospital , Guandong 523018. P. R. China [Abstract] Objective: To investigate the value of MR perfusion imaging in evaluating the curative effect of interven- tional treatment of liver cancer. Methods: Thirty-six patients underwent MR perfusìon imaging after transcatheter arterial chemoembolization and radiofrequency ablation. The quantitative results were compared between carcinoma residue and be- nign tissue. And the diagnostic accuracy was judged. Results: There was a significant difference in mean MSI between tumor residue and the benign enhancement area. The time-signal intensity curve of residual tumor was observed to ascend rapidly to reach the peak.whereas that of the enhancement tissue ascended slowly to reach the pea k. The sensitivity and specificity of PWI on detection of residual or recurrent tumor was O. 89 and O. 73 respectively. Conclusion:PWI is a very sensitive ima- ging technique that can be used to distinguish liver tissue condition after interventional tre