气-质谱联用法快速测定工作场所空气中多组分农药中毒.pdfVIP

实用预防医学 2008年6月 第 15卷 第3期 Practical Preventive Medicine，Jun．2008，Vol 15，No．3 633 文章编号：1006—3110(2008)03—0633—05 【论 著 】 气一质谱联用法快速测定工作场所 空气中多组分农药中毒 谭爱军，陈剑刚，张彩虹，白艳铃，黄辉涛 摘要： 目的 建立工作场所空气中有机磷农药、有机氯农药、氨基甲酸酯农药、拟除虫菊酯类农药共42种组分的快 速测定方法。 方法 采用固体吸附剂采集空气中多种混合农药毒物，用1：1丙酮一正己烷解吸后以DB一35 ms为分离 柱、气相色谱一质谱仪联用分析测定。 结果 所有组分彼此完全分离，能同时予以定性确认；42种有机农药在一定浓 度范围内线性关系良好，相关系数R≥0．99；最低检出限远低于职业化学中毒现场剂量水平。8种代表性农药组分解吸效 率为86．3％～98．5％。 结论 本方法具有高选择性、灵敏度和准确度，完全满足工作场所空气中多种农药中毒的快速 定性定量测定。 关键词：有机农药；工作场所；空气；GC／MS；测定 中图分类号：R一331 文献标识码：A Quick Determination of Multi—organic Pesticide Components(OPs)in Workplace Air by Gas Chromatography—mass Spec· trometry TAN Ai jun，CHEN dian—gang，ZHANG Cai—hong，et a1．(Zhuhai Municipal Center for Disease Control Prevention，Zhuhai 519000，Guangdong) Abstract： Objective To establish a gas chromatography—mass spectometry method for rapid determination of 42 of OCPs，OCs，carbamates and pyrethroids pesticides in the air in a workplace． Methods Forty— two OPs in the a ir were absorbed by various solid sorbents and solvent desorption using 1+1 acetone／heaxane，then separated by GO with an DB一 35ms capillary column and analyzed by MS． Results The results showed that all Ops were separated completely each oth— er，simultaneously identified and quantified．The correlation coefficient of allI calibration curves was good(≥0．99)，and be— tween defined cOncentratiOn range．The Iimit of detection of 42 OPs was much lower than poisoning dosage level in the work— place air，8 kinds of typical OPs with the desorption efficiency of 86．3％～98．5％． Conclusions This method is selective， sensitive，accurate，and applicable to qualify and quantify m‘xtures of OPs in the air at a workplace． Key words： Organic pesticides；Workplac