早期乳腺癌应用保乳手术治疗效果临床观察.docVIP

早期乳腺癌应用保乳手术治疗效果临床观察【摘要】 目的 早期乳腺癌分别应用保乳手术与改良根治手术进行治疗,观察美容效果、生存率及生活质量的不同。方法 选取我院收治的260例早期乳腺癌患者,分为观察组与对照组,观察组共130例,应用保乳手术治疗,对照组共130例,应用乳腺癌改良根治手术治疗,二组患者术后均进行治疗,关注患者的美容效果、生存率及生活质量。结果 观察组患者术后的美容的优良率是58.46%,术后5年随访,二组患者的生存率差别无统计学意义,而观察组患者生活质量评分明显高于对照组。结论 早期乳腺癌患者应用保乳手术治疗,美容效果明显,并能达到与根治手术相同的5年生存率,患者生活质量高,临床中可以应用。 【关键词】 早期乳腺癌;保乳手术;预后;生活质量 The clinical observation of breast-conserving surgery in early breast carcinoma WU Jingjing,ZHANG Peng-yu,TAN Qing-xia,et al.First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China 【Abstract】 Objective To observe the curative effect,cosmetic effect and life quality in early breast carcinoma by breast-conserving surgery.Methods 260 cases with early breast carcinoma were divided into two groups.The observation group(130 cases)was intervened by breast-conserving surgery.The control group was(130 cases)was intervened by modified radical mastectomy.We pay attention to cosmetic effect,survival rate and life quality.Results The excellent and good rate of cosmetic effect were 58.46% in the observation group.The survival rate were not obviously significant after operative 5 years in the two groups.The scores of life quality were obviously higher in the observation group.Conclusion The prognosis are not different in the breast-conserving surgery and modified radical mastectomy.But the surgery of breast-conserving can improve the cosmetic effect and life quality,is worthy of being recommended in clinical treatment. 【Key words】Early breast carcinoma; Breast-conserving surgery; Prognosis; Life quality 作者单位:450052郑州大学第一附属医院 乳腺癌作为一种全身性疾病,手术的大小并不能决定其远期生存率。保乳手术与术后放化疗结合,是治疗早期乳腺癌的重要方法。本文对早期乳腺癌分别应用保乳手术与乳腺癌改良根治术进行治疗,关注其美容情况、生存率及生活质量的差别。 1 资料和方法 1.1 一般资料 收集早期乳腺癌患者。纳入标准:①外周型单发肿瘤,肿瘤直径≤3 cm,肿瘤和乳晕间距≥2 cm;②患者乳房有适当体积,术后能保持外观效果;③肿瘤未发生远处转移。本组共260例,年龄37~65岁,随机分为观察组与对照组,各130例。观察组与对照组患者在年龄、发病时间及肿瘤大小等相关因素的比较中,差别无统计学意义,具有可比性。 1.2 手术方法 观察组治疗方法:原发灶行肿块切除、乳腺区段或象限切除,切缘距肿瘤1 cm,术中冰冻切片证实为原位癌者不行腋淋巴结清除术,伴有早期浸润时行腋窝淋巴结清除术。于切缘的内、外、上、下、基底部及乳头方向