贺勇fMRI研究设计和论文写作.pptVIP

* 研究设计与论文写作 贺永 北京师范大学认知神经科学与学习 国家重点实验室 一个“好”的研究 ? ? ? ? ? 原创性/创新性 Originality/Creativity 具有重要性 Significance 具备可行性 Feasibility 可重复性 Reproducibility/Reliability 发表后引起关注（正面或者负面）Influence/impact: 5-10 years 作者、编辑、审稿人、读者 科学研究的步骤-作者 ? ? ? ? ? ? ? ? ? ? 选题 Selecting and formulating research problem 检索文献Surveying literature 建立假说Developing hypotheses 设计实验Designing experiment 采集数据Collecting data 处理和分析数据Processing and analyzing data 检验假说Testing hypotheses 解释结果Interpreting results and generalization of results 结论Making conclusion 写作 Paper writing 审稿及发表(编辑、审稿人、读者) ? 投稿 ? 修改 ? 出版 “This study was the first to derive a structural network of the human brain on the basis of correlations in cortical grey matter thickness measured using MRI.” (Bullmore and Sporns, Nat Rev Neurosci 2009) Citation: 137 (from ISI) ? Reviewer 1: “This is an interesting well-written and creatively conceived paper showing for the first time that human brain anatomical connectivity may be topologically organized according to small world principles.” ? Reviewer 2: “This paper deals with an important and very significant research area, the characterization of the anatomical network of long-range connections in the human brain. This crucial data set is currently lacking and any progress towards a more complete anatomical description of the human cortex is highly desirable. The paper attempts to address this issue by using a novel and potentially interesting approach towards mapping anatomical pathways and provides an analysis of the resulting network.” Structural MRI-based Brain Connectome Analysis ? ? ? ? ? ? ? ? Methods (Chen et al., Cereb Cortex 2009; Sanabria-Diaz et al., NeuroImage 2010) Normal development (Fan et al., NeuroImage 2011) Normal aging (Wu et al., Hum Brain Mapp 2011; Zhu et al., Neurobiology of Aging 2011; Chen et al., NeuroImage 2011) Alzheimer’s disease (He et al., J Neurosci 2008; Yao et al., PLoS Computational Biology 2010) Multiple sclerosis (He et al., Bra