可吸收人工脑膜预防窦镰旁大型脑膜瘤术后出血的临床分析 潘凉泽1 .doc

可吸收人工脑膜预防窦镰旁大型脑膜瘤术后出血的临床分析 潘凉泽1,谢延风1,石全红1,张 超1,陆 波1,明 雪２ （400016 重庆，重庆医科大学附属第一医院神经外科1；401331 重庆，重庆医科大学附属大学城医院妇产科2） [摘要] 目的 探讨可吸收人工脑膜预防窦镰旁大型脑膜瘤术后出血的临床应用价值。方法 分析2011年9月至2014年11月重庆医科大学附属第一医院采用可吸收人工脑膜填塞窦镰旁大型脑膜瘤腔（肿瘤最大直径大于5cm）预防术后出血的患者临床资料，选取39例作为实验组；选取我院同期采用传统明胶海绵填塞窦镰旁大型脑膜瘤腔（肿瘤最大直径大于5cm）预防术后出血的39例作为对照组。比较两组术后瘤腔坍塌程度、术后出血、颅内压变化、住院时间长短及3个月随访功能恢复情况。结果 实验组术后瘤腔坍塌程度（21±6.2）%；术后出血2例；颅内压（14.97±4.58） mmHg；住院时间（11.12±1.54）d；3个月随访功能状态：恢复良好37例、恢复较差2例。对照组术后瘤腔坍塌程度显著大于实验组(P ＜0.O5)，术后出血显著多于实验组(P ＜0.O5)，颅内压显著高于实验组(P ＜0.O5)，住院时间显著长于实验组(P ＜0.O5)。3个月随访功能状态明显差于实验组(P ＜0.O5)。结论 可吸收人工脑膜较明胶海绵在填塞窦镰旁大型脑膜瘤腔方面作用相似，更有术后出血少、水肿轻、住院时间短、预后佳等优势，有一定临床应用价值。 [关键词] 可吸收人工脑膜；窦镰旁大型脑膜瘤；术后出血 [中图法分类号] [文献标志码] A Clinical research of absorbable artificial dura mater on preventing Postoperative hemorrhage in Large parasagittal and falcine meningiomas Pan Liangze1 Xie Yanfeng1 Shi Quanhong1 Zhang Chao1 Lu Bo1 Ming Xue2（1Department of Neurosurgery, the First Affiliated Hospital of Chongqing Medical University,chongqing 400016,China；4Obstetrics and Gynaecology, University-Town Hospital of Chongqing Medical University, chongqing 400016,China)Abstract] Objective To observe the clinical effects of absorbable artificial dura mater on preventing postoperative hemorrhage in Large parasagittal and falcine meningiomas Methods Analysis the clinical data of patients with large parasagittal and falcine meningiomas (maximum tumor diameter?greater than 5cm) from 2011?September?to 2014?November in First Affiliated Hospital of Chongqing Medical University ,?39 patients using absorbable?artificial dura?mater on preventing postoperative hemorrhage were selected?as the experimental group. At the same time, 39 patients using gelatin sponge on preventing postoperative hemorrhage were selected as control group.Compare the degree of postoperative tumor cavity collapse, postoperative hemorrhage, intracranial pressure , hospital stay and?functional recovery after?3?months between th