evaluation of a single-shot thick-slab turbo spin - 第三军医大学学报.DOC

应用单层厚块单次激发快速自旋回波序列蔡萍 黎川 王健* 黄学全 谢兵 王新 周代全 何强 巫北海 第三军医大学附属西南医院放射科（400038） 摘要 目的本研究利用磁共振成像的原理采用单次激发厚层快速自旋回波(single-shot turbo spin echo，SSTSE)重T2加权序列行磁共振胎儿成像(magnetic resonance fetography，MRF)，评价其作为胎儿三维重建的一种替代方法的可性材料和方法2006年4月至2008年2月间因产前超声筛查诊断或怀疑胎儿存在先天性缺陷以及染色体检查异常的孕妇164例，169胎儿，羊水正常137例，其中中孕38例，晚孕99例，羊水过多18例，羊水过少9例羊水正常者头位胎104例，臀位胎29例横位胎4例常规胎儿MRI检查基础上行MR对MR图像进行质量评价，分析图像质量与孕周、胎位和羊水的关系结果所有胎儿常规扫描和MR成像均一次成功。胎儿体内的含液器官病理性扩张萎陷，胎儿病理性积液，囊性，，以及母体和囊性病变穿透胎儿表面后同时显示。MR成像质量与胎儿孕龄、胎位、羊水量无统计学差异p0.05)。结论MRF提供了一种具有三维立体感的胎儿整体图像，能在一幅图像上同时捕捉胎儿的解剖和病理，具有快速、多方位、多视角、多次重复优质成像的特点，可以作为胎儿三维成像的一种替代方法。关键词：诊断成像胎儿磁共振成像成像技术prenatal visualization of fetal anomaly with a single-shot thick-slab turbo spin-echo sequence CAI Ping, LI Chuan, WANG Jian*, HUANG Xue-Quan, XIE Bing, WANG Xin, ZHOU Dai-Quan, HE Qiang, WU Bei-Hai Department of Radiology, Southwest Hospital, The Third Military Medical University, ChongQing, 400038 China Abatract Objectives: To analysis the quality of magnetic resonance fetography imaging with a single-shot thick-slab turbo spin-echo sequence. And to evaluate the potention of MRF in fetal magnetic resonance (MR) as an alternative to three-dimensional reconstructions. Materials and Methods: From april 2006 to february 2008, 169 fetal MR examinations obtained for various indications (18th to 40+3th gestational weeks) on a 1.5 T unit using a phased-array body surface coil after informed consent. Using our conventional protocol, this included thin multislice T2-weighted HASTE and true-FIST sequence and T1-weighted 2D FLASH sequence. A single-shot thick-slab (20~100 mm) turbo spin-echo was added to our conventional protocol. MRF was evaluated the relationship of the quality of imaging with gestational age, fetal position, amount of amniotic fluid. Results: All our conventional protocol and singl-shot thick-slab turbo spin-echo were performed. On images obtained with this method, the whole fetus could be recognized at once. Fetal surface normal and abnormal structures and fetal extremiti