高强度聚焦超声消融滋养动脉治疗子宫肌瘤的临床价值-声学技术.pdf

第 29 卷第 6 期 声 学 技 术 Vol.29, No.6 2010 年 12 月 Technical Acoustics Dec., 2010 高强度聚焦超声消融滋养动脉治疗 子宫肌瘤的临床价值 姜立新，沈国芳，郭 倩，张晓君，王 燕，胡 兵 (上海交通大学附属第六人民医院超声医学科，上海 200233) 摘要： 目的：探讨高强度聚焦超声消融滋养动脉治疗子宫肌瘤的可行性及有效性。方法：47 例直径 4~10cm 肌壁间 肌瘤，高强度聚焦超声治疗前通过彩色多普勒及超声造影确定肌瘤滋养动脉的蒂，对该区域进行消融，观察治疗前 后肌瘤内部彩色多普勒及超声造影等影像学变化、随访临床症状及并发症。结果：治疗后肌瘤体积有不同程度的缩 小，瘤体假包膜环状血流信号消失，肌瘤内部处于持续无灌注状态，部分患者临床症状消失或明显改善。结论：HIFU 消融滋养动脉治疗子宫肌瘤能够缩短治疗时间，减少并发症，是一种微创和有效的方法。 关键词：高强度聚焦超声(HIFU) ；子宫肌瘤；滋养动脉 中图分类号：TB559 文献标识码：A 文章编号：1000-3630(2010)-06-0603-04 DOI 编码：10.3969/j.issn1000-3630.2010.06.011 The clinical value of the leiomyoma treatment by ablating the nourishing artery with high intensity focused ultrasound JIANG Li-xin, SHEN Guo-fang, GUO Qian, ZHANG Xiao-jun, WANG Yan, HU Bing (Shanghai Jiaotong University affiliated Sixth People‘s Hospital, Shanghai 200233, China) Abstract: Objective: To study the clinical value of the leiomyoma treatment by ablating the nourishing artery with high intensity focused ultrasound. Methods: Before HIFU treatment, the pedicle origins in the false capsule of the leiomyoma are determined by CDFI and contrast-enhanced ultrasound for 47 cases of leiomyomas with 4~10cm diameter. HIFU treatment is carried out in this focal region. The changes of the presentation images of CDFI and contrast-enhanced ultrasound before and after HIFU treatment are detected to evaluate the effectiveness of HIFU treatment. The changes of the clinical symptoms and complications are followed up. Results: The volume of the leiomyoma decreases gradually after HIFU treatment. A annular blood flow signals of pseudocapsule in tumor body disappears with the