电针及阿米替林治疗抑郁症对照观察.docVIP

电针及阿米替林治疗抑郁症对照观察［摘要］目的：探讨比较电针与阿米替林对抑郁症的疗效。方法：将52例抑郁症患者随机分为2组，各26例，分别给予电针和阿米替林治疗，疗程6周，用HAMD量表评分和4级标准评定疗效。结果：电针组愈显率61.54%，药物对照组65.38%，显效时间对照组早于电针组；副反应对照组较电针组明显，特别是心电图改变。结论：电针与阿米替林对抑郁症均有较好疗效，且两者间无显著差异，电针还适合于治疗老年或伴有心血管疾病的抑郁症患者。 ［主题词］电针；阿米替林/治疗应用；抑郁症/针灸疗法；针药并用 Control Observation on Electroacupuncture and Amitriptyline for Treatment of Depression Kang Bo, Zhang Pinggen, Xiong Shengcai, et al. (Yichun Municipal Third People?s Hospital, Jiangxi 336000, China) ［Abstract］Purpose To compare therapeutic effects of electroacupuncture and Amitriptyline on depression. Methods 52 cases of depression were randomly divided into 2 groups, 26 cases in each group. They were treated respectively with electroacupuncture and Amitriptyline for 6 courses, and HAMD Rating Scale and a criterior of assessment for 4-grade therapeutic effects were adopted. Results The markedly effective rate was 61.54% in the electroacupuncture group and 65.38% in the Amitriptyline group. The Amitriptyline produced earlier the marked effect, but adverse effects of Amitriptyline were more obvious, particularlly changes of electrocardiogram, as compared with electroacupuncture.Conclusion Electroacupuncture and Amitriptyline have better therapeutic effect and also, electroacupuncture is suitable to the patients of senile depression or accompanied with cardiovascular diseases. ［Key words］Electroacupuncture;Amitriptyline/ther use;Depression/acup ther;Acupuncture Medication Combined 为进一步探讨电针的抗抑郁作用，1997年4月～2001年3月笔者用电针治疗抑郁症，并与抗抑郁药阿米替林进行了临床对照观察，现将结果报告如下。 1临床资料 1.1一般资料 选自在我院住院的52例患者，随机单盲法，以住院号的单双号进行编组，单号为治疗组，双号为对照组，各26例。治疗组男19例，女7例；年龄18～58岁，平均32±10岁；本次病程2.8±1.3月。单相抑郁症16例，双相情感障碍抑郁相10例。对照组男17例，女9例；年龄18～56岁，平均34±11岁；本次病程2.7±1.6月。单相抑郁症17例，双相情感障碍抑郁相9例。两组病人在性别、年龄、病程及疾病分型等方面经检验差异无显著性意义(P0.05)。 1.2病例选择 (1) 符合中国精神疾病分类方案与诊断标准(CCMD-2-R)抑郁症或双相情感障碍抑郁相的诊断标准。(2)年龄18～58岁。(3)汉密顿抑郁量表(HAMD)评分≥18分。(4)排除严重心、肝、肾疾病及癫痫、青光眼病人。(5)没有使用或停用其它抗抑郁药1周以上。 2治疗方法 2.1电针组 主穴：百会、印堂、脑户、前顶、后顶。配穴：忧郁寡言加哑门，天突；焦虑烦躁加神道、三阴交、太