多微孔胺基树脂的制备及其对胆红素的吸附性能 - 马光辉组.pdf

生 物 工 程 学 报 Chin J Biotech 2009, April 25; 25(4): 611-617 Chinese Journal of Biotechnology ISSN 1000-3061 cjb@ © 2009 Institute of Microbiology, CAS CSM, All rights reserved 生物技术与方法 1,2 1 1 1 2 肖元丕 , 曲剑波 , 王佳兴 , 马光辉 , 赵会英 1 , 100080 2 , 100029 : 采用悬浮聚合法制备了一定尺寸的多微孔聚苯乙烯(PS)微球, 然后通过 Friedel-Crafts 反应(用氯乙酰氯替代了 有致癌性的氯甲醚)和胺化反应得到新型的胺基树脂, 并对反应条件进行了优化。结果表明, 利用最优化条件制备的胺 基树脂, 其离子交换容量为4.1587 mmol/g 。考察了新型树脂对胆红素的吸附性能, 其吸附量最大可达30.85 mg/g, 吸附 率可达80%。 : 悬浮聚合, 氯乙酰化反应, 多乙烯多胺固载, 胆红素静态吸附 Preparation of aminated porous resin and for bilirubin adsorption 1, 2 1 1 1 2 Yuanpi Xiao , Jianbo Qu , Jiaxing Wang , Guanghui Ma , and Huiying Zhao 1 National Key Laboratory of Biochemical Engineering , Institute of Process Engineering , Chinese Academy of Sciences, Beijing 100080, China 2 College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China Abstract: Polystyrene microspheres (PS) were successfully prepared by suspension polymerization processes. Chloroacetylated polystyrene has been prepared by Friedel-Crafts acetylation of PS with chloroacetyl chloride. In this report, carcinogenic compound (chloromethylether etc.) was avoided. The effects of solvent, catalyst, acylating agent and reaction time were studied. Novel adsorption resins were obtained by synthesis of chloroacetylated polystyrene with amine. The