A型肉毒毒素治疗鱼尾纹对眉下垂矫正.docVIP

A型肉毒毒素治疗鱼尾纹对眉下垂矫正[摘要]目的：探讨Ａ型肉毒毒素在治疗鱼尾纹时对眉下垂的矫正效果。方法：随机选择单纯作鱼尾纹治疗者为研究对象，采用Ａ型肉毒毒素对称性多点注射法治疗鱼尾纹，观察除皱效果，并测量治疗前后内眦点、瞳孔、外眦点到相应眉上缘的垂直距离。结果：本组共9例，18侧，治疗前内眦点、瞳孔、外眦点到相应眉上缘的垂直距离分别为（3.17±0.21）cm，(2.43±0.24)cm，（2.92±0.44）cm，治疗2周后的距离分别为（3.18±0.21）cm，（2.43±0.23）cm，(3.14±0.45)cm(P0.01)，除皱有效率为100％。结论：Ａ型肉毒毒素在去除鱼尾纹时对矫正眉下垂具有良好效果。 [关键词]A型肉毒毒素；鱼尾纹；眉下垂 [中图分类号]R622[文献标识码]A[文章编号]1008-6455（2008）06-0818-02 Effects of correcting brow ptosis in the treatment of crow’s feet by botulinum toxin A LI Gao-feng,Tan Jun,Zhong Qian,Zou Bo-sheng,Li Bo，Luo Ming-can （Department of Plastic and Cosmetic Surgery, the People’s Hospital of Hunan Province,Changsha 410005, Hunan，China） Abstracts:ObjectiveTo investigate the effect of correcting brow ptosis in the treatment of crow’s feet by botulinum toxin A.MethodsPatients simple for the treatment of crow’s feet were randomly enrolled in this study.The crow’s feet was treated with symmmtry and multi-point injection of botulinum toxin A.The effect of treating crow’s feet was observed.Vertical dimensions extending from medial canthus,midpupil,lateral canthus to the superior margin of brow were measured at prior-treatment and post-treatment.ResultsNine cases were enrolled .The vertical dimensions extending from medial canthus,midpupil,lateral canthus to the superior margin of brow were (3.17±0.21）cm，（2.43±0.24）cm，（2.92±0.44）cm at prior-treatment,and（3.18±0.21）cm，（2.43±0.23）cm，（3.14±0.45）cm(P0.01) at two weeks post treatment respectively.The effective rate of treating wrinkles was 100%.ConclusionBrow ptosis can be effectively corrected in the treatment of crow’s feet by botulinum toxin A. Key words:botulinum toxin A;crow’s feet;brow ptosis 鱼尾纹的出现是眶周老化的重要表现之一，眼轮匝肌的收缩是产生鱼尾纹的直接原因。A型肉毒毒素能特异性地与周围胆碱能神经元的突触前膜结合，抑制乙酰胆碱的释放，从而降低肌力，因而广泛应用于去除面部动力性皱纹，临床应用表明A型肉毒毒素抑制眼轮匝肌收缩，去除鱼尾纹效果良好[1]。眉下垂影响人的精神面貌，给人以疲劳困倦之感，临床上多采用提眉术矫正，但需要一定的恢复时间，且有留下瘢痕的风险。因眼轮匝肌收缩形成向下的拉力亦是眉下垂的重要原因[2]，因此A型肉毒毒素在治疗鱼尾纹时可能对眉下垂具有矫正效果，现将临床研究报道如下。 1临床资料 随机选择单纯作鱼尾纹治疗者为研究对象，共9例，18侧，年龄为29～48岁，平均