病程超过1周重度以上突发性聋短期疗效分析.docVIP

病程超过1周重度以上突发性聋短期疗效分析 黄开来，康厚墉，钟时勋，钱 怡，胡国华，黄江菊 (400016重庆，重庆医科大学附属第一医院耳鼻咽喉科) [摘要] 目的 了解未规范治疗或治疗效果欠佳的、病程超过1周的重度以上突发性聋的短期疗效。方法 对住院的76例共77耳病程超过1周的重度以上突发性聋患者的临床资料进行回顾性分析。根据入院前听阈均值(pure tone average，PTA)分为重度聋组、极重度聋组及全聋组，按发病至入院时间将重度聋、极重度聋组又分为7(13、14(29、≥30 d，对各组的预后进行比较。结果 重度突发性聋组、极重度聋组、全聋组治疗后PTA改善分别为（17.3±13.6）、（21.0±17.7）、（12.4±9.1）dB，治疗前后PTA差异均有统计学意义（P0.05），但组间PTA改善差异无统计学意义（P0.05）；PTA≤50 dB的百分率分别是37.1%、12.9%、0%，组间差异有统计学意义（P 0.05）。重度突发性聋组7～13、14～29、≥30 d PTA≤50 dB的百分率分别为44.4%、14.3%、20%，而极重度聋组分别是16%、0%、0%。结论 对未规范治疗或治疗效果欠佳的病程超过1周的重度与极重度突发性聋患者进行治疗仍有意义,但全聋患者及病程超过2周的重度以上突发性聋疗效欠佳。 [关键词] 突发性聋；预后；临床研究 [中图法分类号] [文献标志码] A Short-term effect of treatment for severe sudden sensorineural hearing loss for at least one weeks Huang Kailai,Kang Houyong,Zhong shixun,Qian Yi,Hu Guohua,Huang Jiangju (Department of Otorhinolarngology-Head and Neck Surgery, First Affiliated Hospital of Chongqing Medical University,Chongqing, 400016,China) [Abstract]Objective To investigate and analyze the significance of treatment in severe sudden sensorineural hearing loss patient ,which without standard treatment or poor treatment effect present for at least one week . Methods We retrospectived 70 patients with severe sudden sensorineural hearing loss (SSNHL) who pure tone average (PTA) threshold was more than 70 dB and presented for at least one weeks and they were admitted to the department of Otorhinolarngology-Head and Neck Surgery.The patients were devided into severe,profound and total SSNHL by the hearing threshold,and further divided into 7-13days,14-29 days ,≥30 days by times from the onset to the our hospital. Results The improvemented in PTA threshold among the severe, profound and total SSNHL groups was separately 17.3±13.6,21.0±17.7,12.4±9.1 dB,the diffrence before and after treatment has statistical significance（P0.05）,but PTA threshold improvement without statistical significance among three groups（P 0.05）. After therapy , the percentage rate of severe, prof