electrospun nanostructured fibers of collagen-biomimetic apatite on titanium alloy实际上电纺纳米纤维在钛合金collagen-biomimetic磷灰石.pdfVIP

Hindawi Publishing Corporation Bioinorganic Chemistry and Applications Volume 2012, Article ID 123953, 8 pages doi:10.1155/2012/123953 Research Article Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy Michele Iafisco,1, 2 Ismaela Foltran,1, 2 Simona Sabbatini,3 Giorgio Tosi,3 and Norberto Roveri1 1 Dipartimento di Chimica “G. Ciamician,” Alma Mater Studiorum Universita di Bologna, Via Selmi 2, 40126 Bologna, Italy ` 2 Dipartimento di Scienze Mediche, Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy ` 3 Dipartimento di Scienze e Tecnologie Chimiche, Universita Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy ` Correspondence should be addressed to Michele Iafisco, michele.iafisco@unibo.it Received 27 July 2011; Accepted 17 October 2011 Academic Editor: Giovanni Natile Copyright © 2012 Michele Iafisco et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Titanium and its alloys are currently the mainly used materials to manufacture orthopaedic implants due to their excellent mechanical properties and corrosion resistance. Although these materials are bioinert, the improvement of biological properties (e.g., bone implant contact) can be obtained by the application of a material that mimics the bone extracellular matrix. To this aim, this work describes a new method to produce nanostructured collagen-apatite composites on tita