benefits from treatment and control of patients with resistant hypertension受益于治疗和控制高血压患者的抵抗力.pdfVIP
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benefits from treatment and control of patients with resistant hypertension受益于治疗和控制高血压患者的抵抗力
SAGE-Hindawi Access to Research
International Journal of Hypertension
Volume 2011, Article ID 318549, 8 pages
doi:10.4061/2011/318549
Review Article
Benefits from Treatment and Control of Patients with
Resistant Hypertension
Michael Doumas,1 Vasilios Papademetriou,2 Stella Douma,3 Charles Faselis,1
Konstantinos Tsioufis,2 Eugene Gkaliagkousi,3 Konstantinos Petidis,3
and Chrysanthos Zamboulis3
1 Veterans Aff airs Medical Center, George Washington University, Washington, DC 20422, USA
2 Veterans Aff airs Medical Center, Georgetown University, Washington, DC 20422, USA
3 2nd Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki,
49 Konstantinoupoleos Street, 54643 Thessaloniki, Greece
Correspondence should be addressed to Michael Doumas, michalisdoumas@yahoo.co.uk
Received 11 October 2010; Accepted 16 November 2010
Academic Editor: A. Gradman
Copyright © 2011 Michael Doumas et al. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
Resistant hypertension is commonly found in everyday clinical practice. However, the risks of resistant hypertension, as well as
the benefits of treatment and control of blood pressure in patients with resistant hypertension remain vaguely clarified. Data from
small clinical studies and observational cohorts suggest that patients with resistant hypertension are at increased cardiovascular
risk, while control of blood pressure offers substantial benefits. It has to be noted however that data from appropriate large
randomized studies are missing, and resistant hypertension remains remarkably understudied. Resistant hypert
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