原创力文档cell membranes composition is defined in er and their restitution proceed by en bloc fusion of er generated transport vesicles细胞膜成分定义在er和归还进行全体er生成运输囊泡的融合.pdfVIP
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cell membranes composition is defined in er and their restitution proceed by en bloc fusion of er generated transport vesicles细胞膜成分定义在er和归还进行全体er生成运输囊泡的融合
Vol.2, No.12, 1437-1447 (2010) Health
doi:10.4236/health.2010.212214
Cell membranes composition is defined in ER and their
restitution proceed by en bloc fusion of ER generated
transport vesicles
Amalia Slomiany*, Bronislaw L. Slomiany
Research Center, University of Medicine and Dentistry of New Jersey, Newark, USA; *Corresponding Author: slomiabr@
Received 28 September 2010; revised 19 October 2010; accepted 25 October 2010
ABSTRACT nents restored [3,10,11]. In the proposed concepts of the
vesicular transport, the endoplasmic reticulum (ER) is
The synthesis of endoplasmic reticulum (ER)-
depicted as a protein synthetic and folding site apart
derived transport vesicles is dictated by the
from its role in the vesicular membrane lipid synthesis
contents and derivation of the cellular cytosol.
and membrane assembly that includes insertion of the
The ER transport vesicles synthesized in the
integral proteins dedicated for the specific vesicle and
presence of gastric epithelial cells cytosol are
destination site. In our view, the independent of each
destined for en bloc fusion with apical epithelial
other lipid assembly into the memb
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