correlation of prefrontal activity measured by near-infrared spectroscopy (nirs) with mood, bdnf genotype and serum bdnf level in healthy individuals前额叶活动的相关衡量近红外光谱(nirs)与心情,bdnf基因型和健康人血清bdnf水平.pdfVIP

correlation of prefrontal activity measured by near-infrared spectroscopy (nirs) with mood, bdnf genotype and serum bdnf level in healthy individuals前额叶活动的相关衡量近红外光谱(nirs)与心情,bdnf基因型和健康人血清bdnf水平.pdf

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correlation of prefrontal activity measured by near-infrared spectroscopy (nirs) with mood, bdnf genotype and serum bdnf level in healthy individuals前额叶活动的相关衡量近红外光谱(nirs)与心情,bdnf基因型和健康人血清bdnf水平

Open Journal of Psychiatry, 2012, 2, 194-203 OJPsych /10.4236/ojpsych.2012.23025 Published Online July 2012 (http://www.SciRP.org/journal/ojpsych/) Correlation of prefrontal activity measured by near-infrared spectroscopy (NIRS) with mood, BDNF genotype and serum BDNF level in healthy individuals 1* 2,3 1 1 1 Daisuke Matsuzawa , Kotaro Takeda , Hiroyuki Ohtsuka , Jun Takasugi , Takashi Watanabe , 1 1 1 4 1 1 Junko Maeda , Saeka Nagakubo , Chihiro Sutoh , Ichiro Shimoyama , Ken Nakazawa , Eiji Shimizu 1Department of Cognitive Behavior Physiology, Graduate School of Medicine, Chiba University, Chiba, Japan 2Clinical Research Center, National Hospital Organization Murayama Medical Center, Tokyo, Japan 3Department of Motor Control and Rehabilitation, ATR Computational Neuroscience Laboratories, Kyoto, Japan 4Section for Human Neurophysiology, Frontier Medical Engineering, Chiba University, Chiba, Japan * Email: dmatsuzawa@faculty.chiba-u.jp Received 25 April 2012; revised 31 May 2012; accepted 9 June 2012 ABSTRACT NIRS measurement, which is not correlated with the individual properties of BDNF. Depression has been known to reduce the prefrontal activity associated with the execution of certain cog- Keywords: Near-Infrared Spectroscopy (NIRS); nitive tasks, although whether a temporarily de-

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