dietary exercise as a novel strategy for the prevention and treatment of metabolic syndrome effects on skeletal muscle function饮食运动作为一种新颖的代谢综合征的预防和治疗策略对骨骼肌的影响函数.pdfVIP

Hindawi Publishing Corporation Journal of Nutrition and Metabolism Volume 2011, Article ID 676208, 11 pages doi:10.1155/2011/676208 Review Article Dietary Exercise as a Novel Strategy for the Prevention and Treatment of Metabolic Syndrome: Effects on Skeletal Muscle Function Wataru Aoi,1 Yuji Naito,2 and Toshikazu Yoshikawa2 1 Laboratory of Health Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan 2 Department of Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan Correspondence should be addressed to Wataru Aoi, waoi@kpu.ac.jp Received 5 January 2011; Revised 29 March 2011; Accepted 2 May 2011 Academic Editor: Maurizio Muscaritoli Copyright © 2011 Wataru Aoi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. A sedentary lifestyle can cause metabolic syndrome to develop. Metabolic syndrome is associated with metabolic function in the skeletal muscle, a major consumer of nutrients. Dietary exercise, along with an adequate diet, is reported to be one of the major preventive therapies for metabolic syndrome; exercise improves the metabolic capacity of muscles and prevents the loss of muscle mass. Epidemiological studies have shown that physical activity reduces the risk of various common diseases such as cardiovascular disease, diabetes, and cancer; it also helps in reducing visceral adipose tissue. In addition, laboratory studies have demonstrated the mechanisms underlying the benefits of single-bout and regular exercise. Exercise regulates the expression/activi