原创力文档development of an instrument to identify symptoms potentially indicative of ovarian cancer in a primary care clinic setting发展乐器识别症状可能表明卵巢癌在初级保健诊所环境.pdfVIP
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development of an instrument to identify symptoms potentially indicative of ovarian cancer in a primary care clinic setting发展乐器识别症状可能表明卵巢癌在初级保健诊所环境
Open Journal of Obstetrics and Gynecology, 2012, 2, 183-191 OJOG
/10.4236/ojog.2012.23037 Published Online September 2012 (http://www.SciRP.org/journal/ojog/)
Development of an instrument to identify symptoms
potentially indicative of ovarian cancer in a primary
*
care clinic setting
M. Robyn Andersen1,2#, Barbara A. Goff2,3, Kimberly A. Lowe1,4
1Molecular Diagnostics Program, Fred Hutchinson Cancer Research Center, Seattle, USA
2School of Public Health, University of Washington, Seattle, USA
3Seattle Cancer Care Alliance, Seattle, USA
4Exponent Health Sciences, Seattle, USA
Email: #rander@
Received 7 June 2012; revised 9 July 2012; accepted 17 July 2012
ABSTRACT 1. INTRODUCTION
Background: Several recently published studies sug- Two recent prospective studies suggest that efforts to
gest that screening for symptoms could improve the identify women with symptoms and assure prompt as-
early diagnosis of ovarian cancer. This report de- sessment for ovarian cancer using currently available
scribes the development of a simple and reliable tests (CA-125 and TVS) could result in earlier diagnosis
method of collecting symptom information in a pri- of ovarian cancer [1,2]. Consistent with evidence to sug-
mary care clinic. Methods: 1200 women, ages 40 - 87, gest that women with ovarian cancer present with symp-
completed several versions of a draft symptom index toms, even when the disease is in its early stages [3-8],
(SI) assessment form during their visits to a primary and advice from the Gynecologic Cancer Foundation, the
care clinic. Factors associated with a positi
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