early intervention in the neurodevelopment of premature infants during the first six months of life在早产儿神经发育的早期干预生命的前六个月.pdfVIP

Neuroscience Medicine, 2011, 2, 104-109 doi:10.4236/nm.2011.22015 Published Online June 2011 (http://www.SciRP.org/journal/nm) Early Intervention in the Neurodevelopment of Premature Infants during the First Six Months of Life 1 2,3 4 5 Irma Alvarado-Guerrero , Adrián Poblano , Erzsebet Marosi , María Corsi-Cabrera , Gloria A. Otero-Ojeda6 1Interdisciplinary Center for Early Intervention, College of High Studies at Iztacala (UNAM), Tlalnepantla, Mexico; 2Clinic of Sleep Disorders, National University of Mexico (UNAM), Mexico City, Mexico; 3Laboratory of Cognitive Neurophysiology, National Institute of Rehabilitation (INR), Mexico City, Mexico; 4Department of Neuroscience, College of High Studies at Iztacala (UNAM), Tlalnepantla, Mexico; 5School of Psychology, National University of Mexico (UNAM), Mexico City, Mexico; 6School of Medicine, University of State of Mexico (UAEM), Toluca, Mexico. Email: drdeaf@ Received October 27th, 2010; revised March 16th, 2011; accepted March 30th, 2011. ABSTRACT Objective: measure the effects of Early Intervention ad modum Katona (EI-K) in high-risk premature infants by means of clinical, neurobehavioral, and neurophysiologic tests. Method : we used the Amiel-Tison neurologic examination, the Bayley Scale of Infant Behavior, and electroencephalography (EEG) recordings at 42 weeks of conceptional age, and after 6 months of treatment EI-K (n = 14) and compared these results with those of a group of infants without early intervention (nEI) (n = 11). Results : we found better performance of infants in EI-K than nEI group after 6 months of treatment in neurologic and behavioral examination measurements, but found no differences in EEG comparisons. Conclusion: our data suggest significant benefit of the use of EI-K program over n-EI