effect of phacoemulsification on intraocular pressure control in primary open angle glaucoma previously treated by trabeculectomy a case-control study晶状体超声乳化吸出眼压控制的效果之前原发性开角青光眼小梁切除术治疗病例对照研究.pdfVIP

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effect of phacoemulsification on intraocular pressure control in primary open angle glaucoma previously treated by trabeculectomy a case-control study晶状体超声乳化吸出眼压控制的效果之前原发性开角青光眼小梁切除术治疗病例对照研究.pdf

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effect of phacoemulsification on intraocular pressure control in primary open angle glaucoma previously treated by trabeculectomy a case-control study晶状体超声乳化吸出眼压控制的效果之前原发性开角青光眼小梁切除术治疗病例对照研究

Open Journal of Ophthalmology, 2012, 2, 14-20 /10.4236/ojoph.2012.22004 Published Online May 2012 (http://www.SciRP.org/journal/ojoph) Effect of Phacoemulsification on Intraocular Pressure Control in Primary Open Angle Glaucoma Previously Treated by Trabeculectomy: A Case-Control Study 1* 2 3 Samir Aziz , Nicky Spiers , Jeffrey Jay 1Moorfields Eye Hospital NHS Foundation Trust, London, England; 2Tennent Institute of Ophthalmology, Gartneval General Hospi- tal, Glasgow, Scotland; 3University of Leicester, Leicester, England. * Email: samiraziz@.uk Received December 26th, 2011; revised January 19th, 2012; accepted February 9th, 2012 ABSTRACT Purpose: To analyse the effect of phacoemulsification on the control of intraocular pressure in primary open angle glaucoma in patients having phacoemulsification after previous trabeculectomy and compare them with a control group who had trabeculectomy alone. Patients and Methods: Twenty one patients (one eye from each) who had phacoemul- sification subsequent to trabeculectomy were identified, and compared with 41 controls. Intraocular pressure, bleb ap- pearance, glaucoma medications, iris manipulation and complications were recorded. Each patient was followed for full 12 months. Failure of control was defined as follows: 1) intraocular pressure 21 mm Hg on medication, or 2) a greater number of glaucoma medications than before phacoemulsification. Results: The post operative change in intraocular pressure in the case group at 12 months was much less than that in the control (p = 0.00 1). The mean intraocular pres- sure had changed from 15.3 mm Hg to 14.7 mm Hg. The control group showed an average intraocular pressure reduc- tion of 6 mm Hg at the last visit (p 0.001). In phacoemulsification group, 19% required 1 or 2 glaucoma medications at one year follow-up vs 19.5% in the control group. In phacoemulsific