补阳还五汤抗脑缺血作用探究进展.docVIP

补阳还五汤抗脑缺血作用探究进展摘 要:近年来脑血管疾病的发病率居各种老年疾病的前3位,其中以缺血性脑血管病居多,并有逐渐上升和年轻化的趋势,严重危害人类健康。脑缺血性疾病的治疗成为人们关注的领域,而补阳还五汤抗脑缺血效应的研究则成为热点。补阳还五汤是王清任用来治疗半身不遂、瘫痿不用诸症的首选方。功效:补气,活血,通络。随着现代化技术的发展及医学与分子生物学、遗传学的相互渗透,补阳还五汤的抗脑缺血作用机制得到了更全面及深入的诠释。从临床和实验研究两方面对补阳还五汤的抗脑缺血作用进行总结概括。 关键词:脑缺血;补阳还五汤;研究进展 中图分类号:R743.31 文献标识码:A 文章编号:1673-7717(2010)01-0072-03 Research Advance of Buyang Huanwu Decoction Treat Cerebral Ischemia Diseases CHEN Dong,YANG Jie?hong (Department of Basic Reedicine,Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang,China) Abstract:Cerebrovascular disorders have been the first three diseases of old age recent years.In which cerebral ischemia diseases account for most part.More and more people are suffering from this kind of diseases,and these patients tend to younger and younger,which leads a huge damage to our healthy.People have paid moreattention to the treatment to cerebral ischemia,the effection of Bu Yang Huan Wu Decoction has become a hot spot in this research area.Bu Yang Huan Wu Decoction is the preferred formula for hemiplagia differentiated as qi deficiency and blood stasis created by WANG Qing?ren.Function:tonify qi,activate blood and dredge col laterals.According to the development of science and technology and the interaction of medicine,molecular biology and genetics,we have learned more about Bu Yang Huan Wu Decoction and its effective function of treating cerebralischemia.The article is a summary of the treatment to cerebrial ischemia by Bu Yang Huan Wu Decoction in clinical and experimental aspects. Key words:Bu Yang Huan Wu decoction:cerebral lschemia;research advance 近年来脑血管疾病的发病率呈逐年上升趋势,其中以缺血性脑血管病居多,脑缺血性疾病包括短暂性脑缺血、脑栓塞、脑梗死等。脑缺血性疾病的治疗成为人们关注的领域,而补阳还五汤抗脑缺血效应研究则成为热点。补阳还五汤是清代名医王清任所创,原方载于《医林改错#8226;下卷#8226;瘫痿论》,是王清任用来治疗半身不遂、瘫痿不用诸症的首选方。药物组成 为:黄芪4两(120g),生当归尾2钱(6g),赤芍1钱半(5g),地龙1钱(3g),川芎1钱(3g),桃仁1钱(3g),红花1钱(3g),水煎服。本方重用黄芪,补益元气,意在气旺则血行,瘀去络通,为君药。当归尾活血通络而不伤血,用为臣药。赤芍、川芎、桃仁、红花协同当归尾以活血化瘀,地龙通经活络,力专善走,周行全身,以行药力,亦为佐药。以下就补阳还五汤住近几年内对脑缺血性疾病的临床及实验研究作一