原创力文档analgesic and anti-inflammatory activities of the methanol extract from pogostemon cablin甲醇提取物的镇痛和抗炎活动广藿香.pdfVIP
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analgesic and anti-inflammatory activities of the methanol extract from pogostemon cablin甲醇提取物的镇痛和抗炎活动广藿香
Hindawi Publishing Corporation
Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 671741, 9 pages
doi:10.1093/ecam/nep183
Original Article
Analgesic and Anti-Inflammatory Activities of
the Methanol Extract from Pogostemon cablin
Tsung-Chun Lu,1 Jung-Chun Liao,2 Tai-Hung Huang,2 Ying-Chih Lin,3 Chia-Yu Liu,4
Yung-jia Chiu,1 and Wen-Huang Peng1
1 Graduate Institute of Chinese Pharmaceutical Sciences, College of Pharmacy, China Medical University, 91,
Hsieh Shih Road, Taichung, Taiwan
2 School of Pharmacy, College of Pharmacy, China Medical University, 91, Hsieh Shih Road, Taichung, Taiwan
3 Department of Optometry, Jen-Teh Junior College of Medicine, Nursing and Management, No. 79-9,
Sha-Luen-Hu, Xi Zhou Li, Hou-Loung Town, Miaoli County 35664, Taiwan
4 Department of Nursing, Jen-Teh Junior College of Medicine, Nursing and Management, No. 79-9,
Sha-Luen-Hu, Xi Zhou Li, Hou-Loung Town, Miaoli County 35664, Taiwan
Correspondence should be addressed to Wen-Huang Peng, whpeng@.tw
Received 1 June 2009; Accepted 14 October 2009
Copyright © 2011 Tsung-Chun Lu et al. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
Pogostemon cablin (PC) is a herbal medicine traditionally applied to treat not only common cold, nausea and diarrhea but also
headache and fever. The aim of this study was to investigate the analgesic and anti-inflammatory properties of standardized PC
methanol extract (PCMeOH) in vivo. Investigations were performed in mice with two analgesic models. One was acetic acid-
induced writhing response and the other formalin-induced paw licking. Th
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