repertoire of protein kinases encoded in the genome of takifugu rubripes曲目的基因组编码的蛋白质激酶takifugu摘要.pdf

Hindawi Publishing Corporation Comparative and Functional Genomics Volume 2012, Article ID 258284, 12 pages doi:10.1155/2012/258284 Research Article Repertoire of Protein Kinases Encoded in the Genome of Takifugu rubripes R. Rakshambikai,1 S. Yamunadevi,1, 2, 3 K. Anamika,1, 4 N. Tyagi,1, 5 and N. Srinivasan1 1 Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India 2 Max Planck Institute for Intelligent Systems (Formerly Max Planck Institute for Metals Research), BioQuant BQ0038, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany 3 German Cancer Research Center, BioQuant BQ0038, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany 4 Department of Functional Genomics and Cancer and Department of Structural Biology and Genomics, Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC), CNRS UMR 7104, INSERM U 964, ´ ´ ´ Universite de Strasbourg, 1 rue Laurent Fries, 67404 Illkirch Cedex, France ´ 5 European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD Cambridge, UK Correspondence should be addressed to N. Srinivasan, ns@mbu.iisc.ernet.in Received 27 November 2011; Revised 14 February 2012; Accepted 28 February 2012 Academic Editor: G. Pesole Copyright © 2012 R. Rakshambikai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Takifugu rubripes is teleost fish widely used in comparative genomics to understand the human system better due to its similarities both in number of genes and structure of genes. In this work we survey the