screening tests of reproductive immunology in systemic lupus erythematosus在系统性红斑狼疮生殖免疫学筛选试验.pdf

screening tests of reproductive immunology in systemic lupus erythematosus在系统性红斑狼疮生殖免疫学筛选试验.pdf

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screening tests of reproductive immunology in systemic lupus erythematosus在系统性红斑狼疮生殖免疫学筛选试验

Hindawi Publishing Corporation Autoimmune Diseases Volume 2012, Article ID 812138, 6 pages doi:10.1155/2012/812138 Clinical Study Screening Tests of Reproductive Immunology in Systemic Lupus Erythematosus Zdenka Ulcova-Gallova,1 Alice Mockova,2 and Miroslava Cedikova3 1 Department of Obstetrics and Gynecology, Faculty of Medicine in Pilsen and University Hospital, University in Pilsen, 30460 Pilsen, Czech Republic 2 Department of Neonatology, Faculty of Medicine in Pilsen and University Hospital, Charles University in Prague, Alej Svobody 80, 30460 Pilsen, Czech Republic 3 Institute of Histology and Embryology, Faculty of Medicine in Pilsen, Charles University in Prague, Karlovarska 48, ´ 30166 Pilsen, Czech Republic Correspondence should be addressed to Zdenka Ulcova-Gallova, ulcova-gallova@email.cz Received 13 June 2012; Revised 30 September 2012; Accepted 30 September 2012 Academic Editor: Hiroshi Okamoto Copyright © 2012 Zdenka Ulcova-Gallova et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Female patients in reproductive age with systemic lupus erythematosus and fertility complications together are observed by rheumatologists, gynecologists, and reproductive immunologists. The paper notes the presence of autoantibodies to zona pellucida, to phospholipids (phosphatidyl serine, phosphatidyl ethanolamine, phosphatidyl inositol, phosphatidyl glycerol, phosphatidic acid, annexin V, beta-2 glycoprotein I, and cardiolipin)

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