大鼠分娩性臂丛损伤模型肱二头肌及前肢爪内肌microRNA表达差异以及正常大鼠肱二头肌及前肢爪内肌神经肌肉接头出生后发育差异.pdf

复旦大学 博士研究生论文 大鼠分娩性臂丛损伤模型肱二头肌与前肢爪内肌microRNA 表达差异以及正常大鼠肱二头肌与前肢爪内肌神经肌肉接 头出生后发育差异 The Differential ProfileofmicroRNAsthe Expression Between andIntrinsic MusclesofRat Biceps Forepaw Modelsof BrachialPlexus OBPPandtheDifferences InjuriesSimulating inPostnatal NeuromuscularJunctions ofthe Development and Intrinsic MusclesinNormalRatForelimb Biceps Forepaw 博士研究生： 潘峰 专 业： 外科学 导 师： 陈亮教授 导师组成员： 顾玉东院士 胡韶楠教授 万方数据 目 录 英文缩略词表················-··········…········…………一·1 中文摘要·····························………···一一．．一一一”··2 英文摘要········一··………·····················………······9 前言····…································………···…·…···15 参考文献···············································………·18 正文…··························································20 第一部分大鼠分娩性臂丛损伤模型肱二头肌与前肢爪内肌··············20 mi croRNh表达谱 前言···…······························-·--·····-···············20 资料与方法··························………····…………·-··21 结果·······················…·……····················……··31 讨论·························-···················…·············42 参考文献·························································46 第二部分大鼠分娩性臂丛损伤模型肱二头肌与前肢爪内肌差异表达······50 microRNAs靶基因及其生物信息学分析 前言···…··········································-············50 资料与方法·············“··········“·--··“·············……··5l 结果·································