地诺前列酮栓及催产素在足月妊娠引产中比较分析.doc

地诺前列酮栓及催产素在足月妊娠引产中比较分析[摘要] 目的:观察地诺前列酮栓与催产素在足月妊娠引产中的效果和安全性。方法:随机抽取两组条件相同的产妇,共180例,阴道内放置地诺前列酮栓栓剂为观察组,静脉滴入小剂量催产素为对照组,每组90例。应用统计学分析比较两组产妇的宫颈Bishop评分、产程进展、顺产率、新生儿评分及产后出血情况。结果:观察组应用地诺前列酮栓12 h后,宫颈Bishop评分明显高于对照组,有非常显著性差异(P0.05)。结论:地诺前列酮栓应用于足月妊娠引产,效果优于催产素静脉滴入,可安全有效地应用于临床工作中。 [关键词] 地诺前列酮栓;催产素;引产;宫颈 [中图分类号] R719.3+1[文献标识码]A [文章编号]1673-7210(2010)01(b)-015-02 The comparison and analysis of Dinoprostone Suppositories and Oxytocin induction of labor in the term pregnancy SU Qin (Department of Obstetrics, Tai’an Central Hospital, Tai’an 271000, China) [Abstract] Objective: To observe the effect and safety of Dinoprostone Suppositories and Oxytocin induction of labor in the term pregnancy. Methods: Two groups of the same conditions, totally 180 cases were randomly selected and divided into two groups, with 90 cases in each group. The observation group was treated with Dinoprostone Suppository, and the control group was treated with intravenous infusion of low dose Oxytocin. Statistical analysis was applied to compare the cervical Bishop score, birth process, normal labor rate, newborn score and post-partum haemorrhage of the two groups. Results: 12 hours after administered Dinoprostone Suppository, the cervical Bishop score of the observation group was significantly higher than that of the control group (P0.05). Conclusion: The effect of Dinoprostone Suppository used in full-term pregnancy abortion is superior to intravenous oxytocin infusion, and it can be safely and effectively used in clinical work. [Key words] Dinoprostone Suppositories; Oxytocin; Induction of labor; Cervix 随着优生优育工作的深入人心,越来越多的产妇妊娠晚期渴望自然顺产,但妊娠晚期宫颈不成熟是影响顺产率的重要原因。传统的催产素静脉点滴引产方法中,对宫颈不成熟的这一部分产妇,往往费时费力,效果一般,导致剖宫产率增高。近2年来,地诺前列酮栓的临床应用明显改善了这一状况,提高了顺产率,提高了产科工作质量。本研究收集我院2009年1～5月180例足月妊娠引产病例,探讨地诺前列酮栓与催产素对晚期妊娠引产的效果及临床意义,现分析如下: 1资料与方法 1.1一般资料 抽取2009年1～5月在我院行地诺前列酮栓引产的90例产妇作为观察组,其中,经产妇12例,初产妇78例。随机抽取同期催产素静脉滴入的90例引产产妇作为对照组,其中,经产妇10例,初产妇80例。两组产妇年龄均为23～38岁,身高154～172 cm,孕37～42周,估计胎儿体重2 600～4 200 g