早期乳腺癌保乳手术及改良根治术临床探究.docVIP

早期乳腺癌保乳手术及改良根治术临床探究[摘要] 目的：探讨保乳手术与改良根治术治疗早期乳腺癌的临床效果。方法：将我院收治的96例早期乳腺癌患者随机分为两组，A组48例行保乳手术，B组48例行改良根治术，分析两组手术时间、术中出血量、住院时间及术后恢复情况。结果：A组手术时间、术中出血量及住院时间明显优于B组，分别为手术时间[（118.52±16.35）min vs（155.87±20.55）min]，术中出血量[（105.26±42.15）ml vs （153.32±51.26）ml]，住院时间[（10.15±2.56）d vs （14.38±3.27）d]，组间差异均有高度统计学意义（t=9.85、3.55、7.06，均P0.05）。结论：保乳手术治疗早期乳腺癌疗效满意，值得推广应用。 [关键词] 早期乳腺癌；保乳手术；改良根治术 [中图分类号] R655.8 [文献标识码] Ａ [文章编号] 1673-7210（2011）11（b）-037-02 Clinical research of breast-conserving surgery and modified radical mastectomy in the treatment of early breast cancer XIA Yongli, MIAO Jingyu, TIAN Zhigang, SUN Shaoqing Department of Surgery, the Third People′s Hospital in Luoyang City, He′nan Province, Luoyang 471002, China [Abstract] Objective: To study the effect of breast-conserving surgery and modified radical mastectomy in treating early breast cancer. Methods: 96 cases with early breast cancer in our hospital were randomly divided into two groups, group A of 48 cases received breast-conserving surgery, group B of 48 cases received modified radical mastectomy, and the operation time, hemorrhage in operation, the length of hospital stay and the healing condition of the two groups were compared. Results: There were significant differences about the operation time [(118.52±16.35)min vs (155.87±20.55)min], hemorrhage in operation [(105.26±42.15)ml vs (153.32±51.26)ml] and the length of hospital stay [(10.15±2.56)d vs (14.38±3.27)d] between two groups (t=9.85, 3.55, 7.06, all P0.05). Conclusion: The effect of breast conserving surgery in treating early breast cancer is satisfactory, so it is recommending for wide application. [Key words] Early breast cancer; Breast-conserving surgery; Modified radical mastectomy 乳腺癌是女性最常见的恶性肿瘤之一，在我国占全身各种恶性肿瘤的7%~10%，呈逐年上升趋势，在国内部分地区已成为女性恶性肿瘤之首位[1]。早期乳腺癌目前主要的治疗方法是保乳手术或改良根治术配合放化疗及内分泌治疗等综合治疗。我院2002年1月~2008年6月收治96例早期乳腺癌患者，疗效满意，现报道如下： 1 资料与方法 1.1一般资料 本组96例均为女性，年龄31~62岁，平均46岁，均无严重急、慢性疾病。绝经前75例，绝经后21例；Ⅰ期31例，Ⅱ期65例；肿瘤均未浸润乳头、乳晕，直径0.05）