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氨基糖甙类(Aminoglycoside)
氨基糖甙类(Aminoglycoside)
Doctor - antibacterial aminoglycoside - Pharmacopoeia
neomycin
Neomycin (Neomin)
[function and application]
This product is aminoglycoside broad-spectrum antibiotics, has a good effect on Gram negative and gram positive bacteria and Mycobacterium tuberculosis. Most sensitive to Escherichia coli, it is more sensitive to Staphylococcus aureus, Bacillus anthracis, Diphtheria Bacillus, bacillus, Proteus and Shigella, and less sensitive to Pseudomonas aeruginosa. Bacteria can cross resistance to this product and streptomycin, kanamycin and gentamicin. Because of its high toxicity, it is generally not used for injection and is only used in oral administration and local application. Oral absorption of little, can be used for the treatment of diarrhea, Escherichia coli induced diarrhea in children with better efficacy. Can also be used in abdominal and intestinal surgery before medication. Local application effect is also good, such as abscess, furuncle, ulcer and burn effect on skin and mucous membrane infection caused by sensitive bacteria are good.
[dosage and usage]
Oral administration, adult 0.5g to 1g/ times, 4 times / day; children 25mg to 50mg/kg per day, 4 times. Topical application, 0.5% drops of eye fluid or ointment, still have 0.1%, 0.5% solution for local use outside.
[side effects]
This product rarely absorbed in the gastrointestinal tract, mainly gastrointestinal reactions, loss of appetite, nausea and increased stool frequency.
Gentamycin sulfate (CHINT sulfate)
Gentamycin Sulfate
(Gentamicin, Ganamycin, Gentalin, Cidomycin)
[function and application]
This product for aminoglycoside antibiotics,
It has antibacterial and bactericidal effects on a variety of gram negative bacteria and positive bacteria. For Pseudomonas aeruginosa, Bacillus pneumoniae, Salmonella, Escherichia coli, Proteus and other gram-negative bacteria and Staphylococcus aureus and so on.
The mechanism of this product is a specific protein and bacterial ribosomal sub
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