antidepressants and violence problems at the interface of medicine and law抗抑郁药和暴力问题的接口医学和法律.pdfVIP

Policy Forum Antidepressants and Violence: Problems at the Interface of Medicine and Law * David Healy , Andrew Herxheimer, David B. Menkes Summary Lilly [1]. The case was tried and settled by the British regulator [4,5]. It Recent regulatory warnings about in 1994, and as part of the settlement is not clear that the review team adverse behavioural effects of a number of pharmaceutical company obtained comparable data for other antidepressants in susceptible documents about drug-induced antidepressants. activation were released into the individuals have raised the profi le of Sources of Data these issues with clinicians, patients, public domain. Subsequent legal cases, and the public. We review available some of which are outlined below, Data presented to regulatory clinical trial data on paroxetine and have further raised the possibility of a agencies. The data submitted by sertraline and pharmacovigilance link between antidepressant use and GlaxoSmithKline on paroxetine for studies of paroxetine and fl uoxetine, violence. review by the Committee on Safety of and outline a series of medico-legal The issue of treatment-related Medicines Expert Working Group are cases involving antidepressants and activation has since then been described as a complete set of data violence.