bone quality an empty term骨质量空项.pdfVIP

Essay Bone Quality: An Empty Term Harri Sievänen, Pekka Kannus, Teppo L. N. Järvinen* lthough the concept of a solution to the classic paradox of fallacy. Basically, BMD refl ects the “bone quality” is at least 15 osteoporosis: while low BMD values bulk of material (bone mass) of which Ayears old [1], the term has are associated with increased relative the bone, as an organ, is made [22]. recently sparked much discussion and risk of fracture at the population BMD thus denotes a lumped measure debate among clinicians and clinical level, the predictive value of BMD in of virtually everything within the researchers [2–5]. At a recent National an individual patient remains quite measured bone site (i.e., bone cross- Institutes of Health conference on marginal [13–15]. And to further sectional size and dimensions, cortical bone quality, the term was defi ned as: support the concept of bone quality, thickness and porosity, trabecular “The sum total of characteristics of the inclusion of increased bone turnover thickness and number, mineralization bone that infl uence the bone’s resistance to in fracture-predicting models has of bone material), but it denotes fracture ” [6]. somewhat improved the ability to nothing specifi cally. Thus, there is predict fracture risk independently of not much left to be accounted for Where Did the Defi nition BMD [8,16–19].