diagnostic accuracy of a prototype point-of-care test for ocular chlamydia trachomatis under field conditions in the gambia and senegal诊断准确性的一个原型现场即时测试眼沙眼衣原体在田间条件下在冈比亚和塞内加尔.pdfVIP

Diagnostic Accuracy of a Prototype Point-of-Care Test for Ocular Chlamydia trachomatis under Field Conditions in The Gambia and Senegal 1 1,2 ´ 3 1 2 Emma M. Harding-Esch , Martin J. Holland , Jean-Franc¸ois Schemann , Sandra Molina , Isatou Sarr , 1 1 4 5 6 Aura A. Andreasen , Chrissy h. Roberts , Ansumana Sillah , Boubacar Sarr , Edward F. Harding , Tansy 1 1 1 Edwards , Robin L. Bailey , David C. W. Mabey * 1 London School of Hygiene and Tropical Medicine, London, United Kingdom, 2 Medical Research Council Laboratories, Fajara, Banjul, The Gambia, 3 Institut de Recherche ´ ´ ´ ´ ´ pour le Developpement (IRD), Dakar, Senegal, 4 National Eye Care Programme, Ministry of Health, Banjul, The Gambia, 5 Programme National de Lutte contre la Cecite, ` ´ ´ ´ Ministere de la Sante, Dakar, Senegal, 6 Ely, United Kingdom Abstract Background: The clinical signs of active trachoma are often present in the absence of ocular Chlamydia trachomatis infection in low prevalence and mass treated settings. Treatment decisions are currently based on the prevalence of clinical signs, and this may result in the unnecessary distribution of mass antibiotic treatment. We aimed to evaluate the diagnostic accuracy of a prototype point-of-care (POC) test, developed for field diagnosis of ocular C. trachomatis, in low prevalence s