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PLoS MEDICINE Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient 1,2 3 4 1 5 2 Ninette Amariglio , Abraham Hirshberg , Bernd W. Scheithauer , Yoram Cohen , Ron Loewenthal , Luba Trakhtenbrot , 1 2 6 7 6 8 Nurit Paz , Maya Koren-Michowitz , Dalia Waldman , Leonor Leider-Trejo , Amos Toren , Shlomi Constantini , Gideon Rechavi1,6* 1 Cancer Research Center, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel, 2 Institute of Hematology, Sheba Medical Center, Tel Hashomer, Israel, 3 Department of Oral Pathology, School of Dental Medicine, Tel Aviv University, Tel-Aviv, Israel, 4 Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America, 5 Tissue Typing Laboratory, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel, 6 Department of Pediatric Hemato-Oncology, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel, 7 Institute of Pathology, Tel-Aviv Medical Center, Tel-Aviv, Israel, 8 Pediatric Neurosurgery, Dana Children’s Hospital, Tel-Aviv Medical Center, and Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel Funding: The authors received no A B S T R A C T specific funding for this study. Competing Interests: The authors have declared that no competing Background interests exist. Neural