the photocatalytic inactivation effect of fe-doped tio2 nanocomposites on leukemic hl60 cells-based photodynamic therapyfe-doped二氧化钛纳米复合材料的光催化失活效应对白血病hl60细胞光动力治疗.pdfVIP

Hindawi Publishing Corporation International Journal of Photoenergy Volume 2012, Article ID 367072, 8 pages doi:10.1155/2012/367072 Research Article The Photocatalytic Inactivation Effect of Fe-Doped TiO2 Nanocomposites on Leukemic HL60 Cells-Based Photodynamic Therapy Kangqiang Huang,1 Li Chen,2 Meixiang Liao,3 and Jianwen Xiong1 1 Laboratory of Quantum Information Technology, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510006, China 2 Department of Physics and Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, China 3 School of Physics and Engineering, Sun Yat-sen University, Guangzhou 510275, China Correspondence should be addressed to Jianwen Xiong, jwxiong@ Received 7 October 2011; Revised 6 December 2011; Accepted 6 December 2011 Academic Editor: Jiaguo Yu Copyright © 2012 Kangqiang Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Fe-doped TiO2 nanocomposites synthesized by a deposition-precipitation method were characterized by X-ray diffraction (XRD), transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS), and UV-vis adsorption spectra and then were taken as a new “photosensitizer” for photodynamic therapy (PDT). The photocatalytic inactivation of Fe-doped TiO2 on Leukemic HL60 cells was investigated using PDT reaction chamber based on LED light source, and the viability of HL60 cells was examined by Cell Counting Kit-8 (CCK-8) assay. The experimental results showed that the growth of leukemic HL60 cells was significantly inhibited by adding TiO2 nanoparticles,