The Science of Oligon Edwards Lifesciences（Oligon爱德华生命科学公司的科学）.pdf

The Science of Oligon Vantex Whitepaper 01 Science of Oligon Written by: M.T. Quinn, M.S. Edwards Lifesciences F.L. Milder, Ph.D. Introduction The U.S. Centers for Disease Control’s Study on the Efficacy of Nosocomial Infection Control researched nosocomial infections (NI) over a ten-year period from 1975 to 1985 and found a 7% incidence of NIs among all U.S. hospital admissions.1 A ten-year trend analysis (1980–1990) reported a tripling in the inci- dence during that period. In 1998, the CDC reported that the trend of increasing nosocomial infection rates has continued unabated. In the United States, approxi- mately two million patients per year develop nosocomial infections.1,2 More than three million patients annually contract NIs in Europe. Of the four most common types of nosocomial infections (bloodstream, surgical site, respiratory tract and urinary tract) all except surgical site infection are generally caused by some sort of catheter or other tube-like invasive medical device.1,2 The risk of infection correlates with the length of time a device is left in place and the