about the impact of low-intensity pulsed electromagnetic fields on bone mineral density and bone histomorphometry（关于低强度脉冲电磁场对骨矿物质密度的影响和骨骼histomorphometry）.docVIP

About the impact of low-intensity pulsed electromagnetic fields on bone mineral density and bone histomorphometry Author: Xu Qiaoling Road Lihua FORCES IN SOUTHWEST Liu Donghuan, before Jane Wu Xiaoming Li Lirong [Keywords] histomorphometry [Abstract] AIM: To investigate the effects of pulsed electromagnetic fields (PEMFs) on bone mineral density (BMD) and histomorphometry in ovariectomized rats. METHODS: Thirtytwo female SD rats were divided randomly into 4 groups: ovariectomy, control, magnetic A, magnetic B. All the rats were operated on the abdomen and the rats of ovariectomy group and magnetic groups (A, B) were ovariectomized. The rats of control group only had sham operation and were not ovariectomized. The rats in both magnetic groups were exposed to 15 Hz PEMFs 6 hours per day, with its pulse duration set to 5 ms. Magnetic group A and group B were exposed to PEMFs with different magnetic intensity, 4 ?10-4 T for group A and 8 ?10-4 T for group B. All the animals were killed 8 weeks after operation and the changes of BMD and histomorphometric properties were observed. RESULTS: The values #8203;#8203;of BMD, trabecular area, trabecular thickness and trabecular number in ovariectomized group significantly decreased, compared with those of the other three groups (P lt;0.05), while the trabecular separation in ovariectomized group increased obviously, compared with magnetic group A and magnetic group B (P lt;0.05. Compared with those of control group, no significant differences were found in the values #8203;#8203;of total body BMD , trabecular area and trabecular number in magnetic group B (Pgt; 0.05. But, statistically significant differences were observed in the values #8203;#8203;of total body BMD and trabecular number between the two magnetic groups (P lt;0.05. CONCLUSION: There are some evident “windoweffects “during the treatment by PEMFs. PEMFs are effective in improving BMD and histomorphometric values #8203;#8203;and are favorable to the trea