体外循环围术期甲状腺激素与肿瘤坏死因子地变化.pdfVIP

华中科技土学同济医学院 ·黜学岔擞。 Tumornecrosis and Plama hormones thyroid variabilityduring factor—Q(TNF-Ⅱ1 bypass(CPB) Cardiopulmonary ABSTRACT that themechanismsserum Study thyroid objeetive：To of hormones CPB．Wetestedtheserumconcentration decreasingduring andTNF·d observed of serurll hormones and effects the thyroid onthem． aprotinin Methods：thirty．six CPBweredivided patientsundergoing intotwo group(n-26)andgroup(n=8， groups，control aprotinin unit were were 2000，000aprotiningivenduringCPB)，Bloodsamples lh andalsoontheIst-and collected afterCPB seventh· before，at sec—day after for day triiodothyronine(TT3)andthyroxine(T4)． operation Results：TheResultsshowed declineofT3and signifieant T4， andafter riseof CPB，A (CP0．01)during SignificantTNF·a@0．01) 24 to was at hoursafter control demonstrated operation．Ascampared riseof