原创力文档a multi-centre, randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinations的多中心、随机对照试验的认知疗法,防止有害遵守命令的幻觉.pdfVIP
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a multi-centre, randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinations的多中心、随机对照试验的认知疗法,防止有害遵守命令的幻觉
Birchwood et al. BMC Psychiatry 2011, 11:155
/1471-244X/11/155
STUDY PROTOCOL Open Access
A multi-centre, randomised controlled trial of
cognitive therapy to prevent harmful compliance
with command hallucinations
1* 2,5 2 3 3 2,5 3
Max Birchwood , Emmanuelle Peters , Nicholas Tarrier , Graham Dunn , Shon Lewis , Til Wykes , Linda Davies ,
Helen Lester4 and Maria Michail1
Abstract
Background: Command hallucinations are among the most distressing, high risk and treatment resistant
symptoms for people with psychosis; however, currently, there are no evidence-based treatment options available
for this group. A cognitive therapy grounded in the principles of the Social Rank Theory, is being evaluated in
terms of its effectiveness in reducing harmful compliance with command hallucinations.
Methods/Design: This is a single blind, intention-to-treat, multi-centre, randomized controlled trial comparing
Cognitive Therapy for Command Hallucinations + Treatment as Usual with Treatment as Usual alone. Eligible
participants have to fulfil the following inclusion criteria: i) ≥16 years; ii) ICD-10 diagnosis of schizophrenia or
related disorder; iii) command hallucinations for at least 6 months leading to risk of harm to self or others.
Following the completion of baseline assessments, eligible participants will be randomly allocated to either the
Cognitive Therapy for Command Hallucinations + Treatment as Usual group or the Treatment as Usual group.
Outcome will be assessed at 9 and 18 months post randomization with assessors blind to treatment allocation. The
primary outcome is compliance behaviour and secondary outcomes include beliefs about voices’ power, distress,
psychotic
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