expression and significance of hlag endometriosis（hlag子宫内膜异位的表达和意义）.docVIP

Expression and significance of HLAG endometriosis Papers network: [Abstract] Objective: To study the expression of human leukocyte antigen G (HLA G) endometriosis eutopic and ectopic endometrial tissue, to explore the role of HLA G molecules, including the development of endometriosis.: streptomycin avidin-peroxidase (SP assay eutopic endometrium of endometriosis patients with 19 cases and 30 cases of ectopic endometrial HLA molecules G expression levels of 30 patients with non uterus the endometrium of patients with endometriosis as controls. Results: endometriosis reign of endometrial and the ectopic endometrial HLA G positive expression rate (42%, 53% were of control group of normal in utero membrane (P lt;0.01, but the endometriosis eutopic endometrium and ectopic endometrium between HLA G positive expression rate of no significant difference (Pgt; 0.05. Conclusions: The abnormal expression of HLA G molecules may including endometriosis the occurrence play a role in the development process. [Keywords] human leukocyte antigen G, endometriosis, immunohistochemistry 0 Introduction Obstetrics and Gynecology endometriosis (endometriosis, referred to within the endometriosis) is the most common illnesses, the incidence rate of 10% to 15% [1], increased gradually in recent years. Studies have shown that endometriosis is an autoimmune disease, its occurrence and the body’s immune response system is closely related to the human leukocyte antigen (HLA) is the human major histocompatibility complex, mostly research classic HLA molecules NEIYI of disease rarely involving non-classical molecular HLA G molecules belonging to the non-classical HLA I molecules involved in immune regulation, mainly as immunosuppressive function. patients reign determination endometriosis and ectopic endometrial tissue molecule HLA G expression to investigate HLA G in endometriosis development. 1 objects and methods 1.1 Objects Samples were obtained from 200 412/200 510 i