computing approximate standard errors for genetic parameters derived from random regression models fitted by average information reml遗传参数的计算近似标准误差来源于reml随机回归模型拟合的平均信息.pdfVIP
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computing approximate standard errors for genetic parameters derived from random regression models fitted by average information reml遗传参数的计算近似标准误差来源于reml随机回归模型拟合的平均信息
Genet. Sel. Evol. 36 (2004) 363–369 363
c
INRA, EDP Sciences, 2004
DOI: 10.1051/gse:2004006
Note
Computing approximate standard errors
for genetic parameters derived
from random regression models fitted
by average information REML
Troy M. Fa,c ∗, Arthur R. Gb,c ,
Julius H.J. van der Wa,c
a School of Rural Science and Agriculture, University of New England, Armidale,
NSW, 2351, Australia
b NSW Agriculture, Orange Agricultural Institute, Orange, NSW, 2800, Australia
c Australian Sheep Industry CRC
(Received 21 October 2003; accepted 9 January 2004)
Abstract – Approximate standard errors (ASE) of variance components for random regression
coefficients are calculated from the average information matrix obtained in a residual maximum
likelihood procedure. Linear combinations of those coefficients define variance components for
the additive genetic variance at given points of the trajectory. Therefore, ASE of these com-
ponents and heritabilities derived from them can be calculated. In our example, the ASE were
larger near the ends of the trajectory.
random regression / heritability / approximate standard error / genetic parameter /
residual maximum likelihood
1. INTRODUCTION
Random regression (RR) has been widely used for genetic analysis of lon-
gitudinal data from many of the major animal breeding industries world wide
and has also been implemented into routine large scale animal breeding ap-
plications [4]. Estimates of derived genetic parameters such as heritability at
given points along the trajectory are commonly published from such studies
and comment is often made about the accuracy and robustnes
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