age and the neural network of personal familiarity年龄和个人熟悉的神经网络.pdfVIP

Age and the Neural Network of Personal Familiarity 1,2,4 . 2. 1 1,3 2 Markus Donix * , Katja Petrowski , Luisa Jurjanz , Thomas Huebner , Ulf Herold , Damaris 1 1 1 1,3 1,4 Baeumler , Eva C. Amanatidis , Katrin Poettrich , Michael N. Smolka , Vjera A. Holthoff ¨ 1 Department of Psychiatry and Psychotherapy, University Clinic Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany, 2 Department of Psychotherapy ¨ and Psychosomatic Medicine, University Clinic Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany, 3 Neuroimaging Center, Department of Psychology, ¨ Technische Universitat Dresden, Dresden, Germany, 4 DZNE, German Center for Neurodegenerative Diseases, Dresden, Germany Abstract Background: Accessing information that defines personally familiar context in real-world situations is essential for the social interactions and the independent functioning of an individual. Personal familiarity is associated with the availability of semantic and episodic information as well as the emotional meaningfulness surrounding a stimulus. These features are known to be associated with neural activity in distinct brain regions across different stimulus conditions (e.g., when perceiving faces, voices, places, objects), which may reflect a shared neural basis. Alt