原创力文档ratio between negative and positive lymph nodes is suitable for evaluation the prognosis of gastric cancer patients with positive node metastasis正面和负面的淋巴结之间的比率是适合评估胃癌患者的预后积极节点转移.pdfVIP
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ratio between negative and positive lymph nodes is suitable for evaluation the prognosis of gastric cancer patients with positive node metastasis正面和负面的淋巴结之间的比率是适合评估胃癌患者的预后积极节点转移
Ratio between Negative and Positive Lymph Nodes Is
Suitable for Evaluation the Prognosis of Gastric Cancer
Patients with Positive Node Metastasis
1 2 1 1 1 3 1
Jingyu Deng , Dan Sun , Yuan Pan , Li Zhang , Rupeng Zhang , Dianchang Wang , Xishan Hao ,
Han Liang1*
1 Gastric Cancer Surgery Division, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China, 2 Institute of
Lung Cancer, General Hospital of Tianjin Medical University, Tianjin, China, 3 Hepatobilliary Cancer Surgery Division, Tianjin Medical University Cancer Institute and
Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China
Abstract
Objective: To date, there is no consensus to evaluate the most appropriate category of the nodal metastasis for precise
predication the prognosis of gastric cancer patients with positive node metastasis after curative surgery.
Methods: We retrospectively analyzed the clinicopathologic characteristics and overall survival (OS) of 299 gastric cancer
patients with positive node metastasis after curative surgery for evaluation the optimal category of the nodal metastasis.
Results: With the univariate and multivariate survival analyses, the depth of primary tumor invasion was identified as the
independent predicators with the OS of 299 gastric cancer patients with nodal metastasis postoperatively, as were the
number of positive lymph nodes (PLNs), the number of negative lymph nodes (NLNs), and the ratio between negative and
positive lymph nodes (RNPL). The RNPL was identified to be more suitable for predication the OS of gastric cancer patients
with positive node metastasis than the ratio between positive and dissected lymph nodes (RPDL)
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