原创力文档reduced quantitative ultrasound bone mineral density in hiv-infected patients on antiretroviral therapy in senegal定量超声骨密度降低感染艾滋病毒的患者接受抗逆转录病毒疗法在塞内加尔.pdfVIP
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reduced quantitative ultrasound bone mineral density in hiv-infected patients on antiretroviral therapy in senegal定量超声骨密度降低感染艾滋病毒的患者接受抗逆转录病毒疗法在塞内加尔
Reduced Quantitative Ultrasound Bone Mineral Density
in HIV-Infected Patients on Antiretroviral Therapy in
Senegal
1 1 2 1 3
Amandine Cournil *, Sabrina Eymard-Duvernay , Assane Diouf , Claire Moquet , Julie Coutherut ,
` 4 ´ 1 3 1 2,5
Ndeye Fatou Ngom Gueye , Cecile Cames , Bernard Taverne , Kirsten Bork , Papa Salif Sow , Eric
Delaporte1, for the ANRS 1215 Study Group
´
1 Institut de Recherche pour le Developpement/University Montpellier 1, UMI 233, Montpellier, France, 2 Regional Research and Training Centre for HIV/AIDS, Fann
´
University Teaching Hospital, Dakar, Senegal, 3 Institut de Recherche pour le Developpement/University Montpellier 1, UMI 233, Dakar, Senegal, 4 Ambulatory Care Unit,
Fann University Teaching Hospital, Dakar, Senegal, 5 Department of Infectious Diseases, Fann University Teaching Hospital, Dakar, Senegal
Abstract
Background: Bone status in HIV-infected patients on antiretroviral treatment (ART) is poorly documented in resource-
limited settings. We compared bone mineral density between HIV-infected patients and control subjects from Dakar,
Senegal.
Methods: A total of 207 (134 women and 73 men) HIV-infected patients from an observational cohort in Dakar (ANRS 1215)
and 207 age- and sex-matched controls from the general population were enrolled. Bone mineral density was assessed by
quantitative ultrasound (QUS) at the calcaneus, an alternative to the reference method (i.e. dual
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