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rotavirus antigenemia in children is associated with viremia儿童轮状病毒antigenemia与病毒血症有关
PLoS MEDICINE
Rotavirus Antigenemia in Children
Is Associated with Viremia
1,2 3 1 4 5 1
Sarah E. Blutt , David O. Matson , Sue E. Crawford , Mary Allen Staat , Parvin Azimi , Berkeley L. Bennett ,
Pedro A. Piedra1, Margaret E. Conner1,2*
1 Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America, 2 Michael E. Debakey Veterans Affairs Medical
Center, Houston, Texas, United States of America, 3 Center for Pediatric Research, Norfolk, Virginia, United States of America, 4 Cincinnati Children’s Hospital Medical Center,
Cincinnati, Ohio, United States of America, 5 Children’s Hospital of Oakland, Oakland, California, United States of America
Funding: This work was supported A B S T R A C T
by National Institutes of Health (NIH)
AI10604, NIH AI24998, NIH
DK030144, the Office of Research
and Development, Medical Research Background
Service, Department of Veterans
Affairs, NIH AI145871, the Gulf Coast Antigenemia is commonly detected in rotavirus-infected children. Although rotavirus RNA
Digestive Disease Center (NIH has been detected in serum, definitive proof of rotavirus viremia has not been shown. We
DK56338), the United States Public
Health Service (N01-AI452252), aimed to analyze a defined patient population to determine if infectious virus could be
Glaser Pediatric Research Network detected in sera from children with rotavirus antigenemia.
Fellowship Award, NIH N01-AI30039,
an interinstitutional grant from
Wyeth-Lederle Vaccines and Methods and Find
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