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scaling up diarrhea prevention and treatment interventions a lives saved tool analysis扩大腹泻的预防和治疗干预措施挽救生命的工具分析
Scaling Up Diarrhea Prevention and Treatment
Interventions: A Lives Saved Tool Analysis
1 1 2 2 1
Christa L. Fischer Walker *, Ingrid K. Friberg , Nancy Binkin , Mark Young , Neff Walker , Olivier
3 4 2 1
Fontaine , Eva Weissman , Akanksha Gupta , Robert E. Black
1Johns Hopkins University Bloomberg School of Public Health, Department of International Health, Baltimore, Maryland, United States of America, 2 Health Section,
Programme Division, United Nations Children’s Fund (UNICEF), New York, New York, United States of America, 3 World Health Organization (WHO), Department of Child
and Adolescent Health, Geneva, Switzerland, 4 Futures Institute, Glastonbury, Connecticut, United States of America
Abstract
Background: Diarrhea remains a leading cause of mortality among young children in low- and middle-income countries.
Although the evidence for individual diarrhea prevention and treatment interventions is solid, the effect a comprehensive
scale-up effort would have on diarrhea mortality has not been estimated.
Methods and Findings: We use the Lives Saved Tool (LiST) to estimate the potential lives saved if two scale-up scenarios for
key diarrhea interventions (oral rehydration salts [ORS], zinc, antibiotics for dysentery, rotavirus vaccine, vitamin A
supplementation, basic water, sanitation, hygiene, and breastfeeding) were implemented in the 68 high child mortality
countries. We also conduct a simple costing exercise to estimate cost per capita and total costs for each scale-up scenario.
Under the ambitious (feasible improvement in coverage of all interventions) and universal (assumes near 100% coverage of
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