screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis葡萄球菌超级抗原基因筛查毫无关联的存在或慢性鼻窦炎、鼻息肉病的严重程度.pdfVIP

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screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis葡萄球菌超级抗原基因筛查毫无关联的存在或慢性鼻窦炎、鼻息肉病的严重程度.pdf

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screening for staphylococcal superantigen genes shows no correlation with the presence or the severity of chronic rhinosinusitis and nasal polyposis葡萄球菌超级抗原基因筛查毫无关联的存在或慢性鼻窦炎、鼻息肉病的严重程度

Screening for Staphylococcal Superantigen Genes Shows No Correlation with the Presence or the Severity of Chronic Rhinosinusitis and Nasal Polyposis ´ ´ 1. 2. 1. 2 1 Frederic Heymans , Adrien Fischer , Nicholas W. Stow , Myriam Girard , Zacharias Vourexakis , 1 3 2 4 5 Antoine Des Courtis , Gesuele Renzi , Elzbieta Huggler , Stefan Vlaminck , Pierre Bonfils , Ranko 6 7 2,3 2 1 Mladina , Valerie Lund , Jacques Schrenzel , Patrice Franc¸ois , Jean Silvain Lacroix * 1 Rhinology-Olfactology Unit, Department of Otorhinolaryngology and ENT Surgery, Geneva University Hospital, Geneva, Switzerland, 2 Genomic Research Laboratory, Infectious Diseases Unit, Department of Internal Medicine, Geneva University Hospital, Geneva, Switzerland, 3 Central Laboratory of Bacteriology, Department of Medical Genetics and Laboratory Medicine, Geneva University Hospital, Geneva, Switzerland, 4 AZ Sint-Jan AV, Bruges, Belgium, 5 Department of ENT Head and Neck Surgery, Georges Pompidou European Hospital, Paris, France, 6 Department of ENT Head and Neck Surgery, Clinical Hospital Center, Zagreb, Croatia, 7 UCL EAR Institute of Laryngology and Otology, London, United Kingdom Abstract Background: Staphylococcus aureus secretes numerous exotoxins which may exhibit superantigenic properties. Whereas the virulence of several of them is well documented, their exact biological effects are not fully understood. Exotoxins may influence the immune and inflammatory state of vari