selective serotonin reuptake inhibitor use is associated with right ventricular structure and function the mesa-right ventricle study选择性5 -羟色胺再摄取抑制剂使用与右心室mesa-right心室结构和功能的研究.pdfVIP
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selective serotonin reuptake inhibitor use is associated with right ventricular structure and function the mesa-right ventricle study选择性5 -羟色胺再摄取抑制剂使用与右心室mesa-right心室结构和功能的研究
Selective Serotonin Reuptake Inhibitor Use Is Associated
with Right Ventricular Structure and Function: The
MESA-Right Ventricle Study
1 2 3 4 5
Corey E. Ventetuolo , R. Graham Barr , David A. Bluemke , Aditya Jain , Joseph A. C. Delaney , W.
6 4 7
Gregory Hundley , Joao A. C. Lima , Steven M. Kawut *
1 Department of Medicine, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America, 2 Department of Medicine, College of
Physicians and Surgeons, and the Departments of Epidemiology and Biostatistics, Mailman School of Public Health, Columbia University, New York, New York, United
States of America, 3 Radiology and Imaging Sciences, National Institutes of Health/Clinical Center, National Institute for Biomedical Imaging and Bioengineering, Bethesda,
Maryland, United States of America, 4 Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America,
5 Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America, 6 Department of Internal
Medicine/Cardiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America, 7 Department of Medicine, Penn
Cardiovascular Institute, and the Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania,
United States of America
Abstract
Purpose: Serotonin and the serotonin transporter have been implicated in the development of pulmonary hypertension
(PH). Selective serotonin reuptake inhibitors (SSRIs) may have a role in PH treatment, but the effects of SS
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