sensitive detection of colorectal cancer in peripheral blood by septin 9 dna methylation assay敏感检测外周血的结肠直肠癌septin 9 dna甲基化分析.pdfVIP
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sensitive detection of colorectal cancer in peripheral blood by septin 9 dna methylation assay敏感检测外周血的结肠直肠癌septin 9 dna甲基化分析
Sensitive Detection of Colorectal Cancer in Peripheral
Blood by Septin 9 DNA Methylation Assay
¨ 1 2 1 3 4
Robert Grutzmann *, Bela Molnar , Christian Pilarsky , Jens K. Habermann , Peter M. Schlag , Hans D.
1 5 6 7 3 3
Saeger , Stephan Miehlke , Thomas Stolz , Fabian Model , Uwe J. Roblick , Hans-Peter Bruch , Rainer
8 7 9 9 9 9
Koch , Volker Liebenberg , Theo deVos , Xiaoling Song , Robert H. Day , Andrew Z. Sledziewski ,
Catherine Lofton-Day9
1 Department of Visceral-, Thoracic- and Vascular Surgery, University Hospital Carl Gustav Carus Dresden, Dresden, Germany, 2 Semmelweis University, Budapest,
¨ ¨ ´
Hungary, 3 Department of Surgery, University Hospital Schleswig-Holstein, Campus Lubeck, Lubeck, Germany, 4 Department of Surgery and Surgical Oncology, Charite
¨
Campus Berlin Buch, Robert-Rossle-Klinik, Berlin, Germany, 5 Department of Gastroenterology, University Hospital Carl Gustav Carus Dresden, Dresden, Germany,
¨ ¨
6 Volklingen Clinic, Volklingen, Germany, 7 Epigenomics AG, Berlin, Germany, 8 Institute of Medical Informatics and Biometrics, Technical University of Dresden, Dresden,
Germany, 9 Epigenomics Inc, Seattle, Washington, United States of America
Abstract
Background: Colorectal cancer (CRC) is the second leading cause
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